OCULAR MANIFESTATIONS OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASES

Abstract

INTRODUCTION: At about 6 weeks of gestation both eyes and kidney start to develop and hence they have a strong connection. As a result, a patient who suffers from any kidney disease end up with different ocular disease manifestation. Many congenital anomalies of kidneys can also present as an ocular syndrome. Autosomal dominant polycystic kidney disease (ADPKD) is an inherited kidney disease, which also manifests numerous eye problems. The study helps to identify the ocular associations with ADPKD with creates an awareness towards frequent eye checkup.AIMs and OBJECTIVES: To report the ocular manifestation of Inherited Renal Disease and to identify and characterize the ocular manifestation among patients diagnosed with inherited renal disease. This is a hospital based Cross sectional study, 61 patients were includedRESULTS: Most common ocular complaint was blurring of vision in 52 (85.24%) patients. After refractive error (55.73%), next most common ocular manifestations are, Arcus senilis (36.10%) and hypertensive retinopathy (34.2%). 39 (63.93 %) had no history of previous eye check-up. Most affected age group was patients aged > 35 – 40 years.CONCLUSION: Ocular manifestations can occur before systemic effects of disease starts to appear, thus identifying characteristic ocular manifestation can give a clinical clue allowing definitive diagnosis without expensive and invasive procedures in early course of disease allowing timely intervention.